Cytology

Pathology
Slides

Date
Event
  • Adequacy
    • SurePath 9, ThinPrep 4
    • Endocervical/transformation component
  • Normal cell
    • Superficial cell
      • Pyknotic
      • Keratohyaline granules (HMCK)
    • Intermediate cells
      • Finely granular chromatin
      • Basic size reference
      • Naked nuclei second half of cycle, bacterial cytolysis
    • Parabasal cell
      • Larger nucleus
      • Granular dense cytoplasm
      • higher N/C ratio
    • Endocervical cells
      • Cytoplasm diffusely vacuolated or granular
      • Polarity, nucleus and mucus
    • Endometrial cell
      • Tight cluster
      • Smaller nucleus
      • Dense heterogeneous apoptotic debris
      • Cytoplasm scant dense vacuolated
      • 3 dimension
  • Nonneoplastic variation
    • Squamous metaplasia
      • Variable N/C ratio
    • Keratotic cellular change
      • Keratohyaline granules in intermediate cells
      • Typical parakeratosis
    • Atrophy
      • Thin, immature basal/parabasal cells only
      • Flat monolayer sheet of parabasal-type cells
      • Preserved nuclear polarity
      • Streaming pattern
      • Atrophic vaginitis, blue blobs
    • Reactive cellular change associated with inflammation (Typical repair)
      • Nulear enlargement
      • Without chromatin change
      • Prominant nucleolus
      • Distinct cytoplasmic border
    • RCC associated with Radiation
      • Bizarre cells
      • Polychromasia
      • Nuclear degeneration, cytoplasmic vacuolization
  • Organisms
    • Trichomonas vaginalis
      • Pear shape
      • Nucleus pale, eccentric
      • Eosinophilic cytoplasmic granules
      • Flagella
    • Fungus Candida
      • Pseudohyphae, budding yeast
      • Spearing, shish kebab
    • Shift in flora s/o bacterial vaginosis
      • Coccobacilli absence of lactobacilli
      • Clue cell
    • Actinomycosis
      • Filamentous organism
      • Acute angles
      • Cotton ball
    • Herpes simplex virus
      • Nuclei ground glass
      • Enhance nuclear envelope peripheral chromatin margination
      • Dense eosinophilic intranuclear inclusion (Cowdry)
      • 3Ms Multinucleation, molding, margination of chromatin
    • Cytomegalovirus
      • Large eosinophilic intranuclear viral inclusions with a prominent halo
      • Small cytoplasmic basophilic inclusion
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Jun Kang
Clinical Assistant Professor of Hospital Pathology

My research interests include pathology, oncology and statistics.